Publications

2019

Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy

Chen Z, Chen JA, Shatunov A, Jones AR, Kravitz SN, …Geschwind DH, …Al-Chalabi A (2019). Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy. Mov Disord. 34(7):1049-1059.

Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders

Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, Bearden CE (2019). Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders. Biol Psychiatry. 10.1016/j.biopsych.2019.06.029. [Epub ahead of print].

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, …Geschwind DH, …Walters JTR (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nat Genet. 51(7):1193.

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

Wong CCY, Smith RG, Hannon E, Ramaswami G, Parikshak NN, …Geschwind DH, …Mill J (2019). Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. Hum Mol Genet. 28(13):2201-2211.

CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes

Fricano-Kugler C, Gordon A, Shin G, Gao K, Nguyen J, Berg J, …Geschwind DH (2019). CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes. Mol Autism. 10():25.

Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility

Won H, Huang J, Opland CK, Hartl CL, Geschwind DH (2019). Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. Nat Commun. 10(1):2396.

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, …Geschwind DH, …Mazmanian SK (2019). Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. Cell. 177(6):1600-1618.e17.

Reduced Prefrontal Synaptic Connectivity and Disturbed Oscillatory Population Dynamics in the CNTNAP2 Model of Autism

Lazaro MT, Taxidis J, Shuman T, Bachmutsky I, Ikrar T, …Geschwind DH, …Golshani P (2019). Reduced Prefrontal Synaptic Connectivity and Disturbed Oscillatory Population Dynamics in the CNTNAP2 Model of Autism. Cell Rep. 27(9):2567-2578.e6.

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

Alim I, Caulfield JT, Chen Y, Swarup V, Geschwind DHGeschwind DH, …Ratan RR (2019). Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell. 177(5):1262-1279.e25.

Gene expression shifts in yellow-bellied marmots prior to natal dispersal

Armenta TC, Cole SW, Geschwind DH, Blumstein DT, Wayne RK (2019). Gene expression shifts in yellow-bellied marmots prior to natal dispersal. Behav Ecol. 30(2):267-277.