Publications

2018

Reliability of human cortical organoid generation

Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, …Geschwind DH, …Pașca SP (2018). Reliability of human cortical organoid generation. Nat Methods. 16(1):75-78.

Widespread RNA editing dysregulation in brains from autistic individuals

Tran SS, Jun HI, Bahn JH, Azghadi A, Ramaswami G, …Geschwind DH, …Xiao X (2018). Widespread RNA editing dysregulation in brains from autistic individuals. Nat Neurosci. 22(1):25-36.

Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology

Nana AL, Sidhu M, Gaus SE, Hwang JL, Li L, …Geschwind DH, …Seeley WW (2018). Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology. Acta Neuropathol. 137(1):27-46.

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, …Geschwind DH (2018). Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nat Med. 25(1):152-164.

Whole genome sequencing in psychiatric disorders: the WGSPD consortium

Sanders SJ, Neale BM, Huang H, … Geschwind DH, … Whole Genome Sequencing for Psychiatric Disorders (WGSPD) (2018). Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nat Neurosci. [Epub ahead of print].

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study

Olsen L, Sparso T, Weinsheimer SM, … Geschwind DH, … Werge T (2018). Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study. Lancet Psychiatry. [Epub ahead of print].

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Schwede M, Nagpal S, Gandal MJ, … Geschwind DH, Morrow EM (2018). Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex. J Neurodev Disord. 10(1):18.

Integrative network analysis reveals biological pathways associated with Williams syndrome

Kimura R, Swarup V, Tomiwa K, Gandal MJ, Parikshak NN, …Geschwind DH, …Hagiwara M (2018). Integrative network analysis reveals biological pathways associated with Williams syndrome. J Child Psychol Psychiatry. 60(5):585-598.

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Gusev A, Mancuso N, Won H, … Geschwind DH, … Price AL (2018). Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat Genet. 50(4):538-548.

Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers

Meeter LHH, Gendron TF, Sias AC, … Geschwind DH, … Lee SE (2018). Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers. Ann Clin Transl Neurol. 5(5):583-597.