Haas R, Margolis MP, Wei A, Yamaguchi TN, Feng J, Tran T, Tozzo V, Queen KJ, Mootor MFE, Patil V, Broudy ME, Tung P, Alam S, Martinez DB, Patel Y, Zeltser N, Hugh-White R, Arbet J, Caggiano C, Shemirani R, Tian M, Thapaliya P, Eloyan L, Chen LO, Ariannejad M, Lajonchere C; UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, UCLA Health IT HPC Team, Regeneron Genetics Center; Pasaniuc B, Bui A, Arboleda VA, Chang TS, Zaitlen N, Spellman PT, Boutros PC, Geschwind DH (2026). Diverse genomes, shared health: Insights from a health system biobank. Cell. In press.
Publications
Psychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia.
Vargas-Gonzalez JC, Dimal N, Cortez K, Heuer H, Forsberg LK, Appleby BS, Barmada S, Bozoki A, Clark D, Cobigo Y, Darby RR, Dickerson BC, Domoto-Reilly K, Galasko DR, Geschwind DH, Ghoshal N, Graff-Radford NR, Grant IM, Irwin D, Hsiung GR, Honig LS, Kantarci K, Léger GC, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman P, Ramos EM, Roberson ED, Rogalski E, Boeve BF, Boxer AL, Rosen HJ, Tartaglia MC; ALLFTD Consortium Investigators (2025). Psychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia. Alzheimer’s & Dementia. 21(2):e14448.
Wang H, Chang TS, Dombroski BA, Cheng PL, Si YQ, Tucci A, Patil V, Valiente-Banuet L, Li C, Farrell K, Mclean C, Molina-Porcel L, Rajput A, De Deyn PP, Le Bastard N, Gearing M, Donker Kaat L, Van Swieten JC, Dopper E, Ghetti BF, Newell KL, Troakes C, de Yébenes JG, Rábano-Gutierrez A, Meller T, Oertel WH, Respondek G, Stamelou M, Arzberger T, Roeber S, Müller U, Hopfner F, Pastor P, Brice A, Durr A, Le Ber I, Beach TG, Serrano GE, Hazrati LN, Litvan I, Rademakers R, Ross OA, Galasko D, Boxer AL, Miller BL, Seeley WW, Van Deerlin VM, Lee EB, White CL 3rd, Morris HR, de Silva R, Crary JF, Goate AM, Friedman JS, Compta Y, Leung YY, Coppola G, Naj AC, Wang LS; PSP Genetics Study Group; Dalgard C, Dickson DW, Höglinger GU, Tzeng JY, Geschwind DH, Schellenberg GD, Lee WP (2025). Copy number variation and haplotype analysis of 17q21.31 reveals increased risk associated with Progressive Supranuclear Palsy and gene expression changes in neuronal cells. Movement Disorders. 40(5):950-961.
Xia W, Morcom L, Xu Z, Lu IL, Wang Q, Hoi KK, Wei M, Zhu K, Jordan G, Tang XY, Gonzalez-Maya J, Mattera VS, Panigrahi SM, Kawaguchi R, Emery B, Franco SJ, Geschwind DH, Popko B, Rowitch DH, Fancy SPJ (2026). Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair. Nature. In press.
Flagan TM, Chu SA, Häkkinen S, Zhang L, McFall D, Heller C, Rohrer JD, Brown J, Lee A, Fernhoff K, Pasquini L, Mandelli ML, Gorno-Tempini ML, Yokoyama JS, Sturm VE, Appleby B, Dickerson BC, Domoto-Reilly K, Foroud T, Geschwind DH, Ghosal N, Graff-Radford NR, Grossman M, Hsiung G-Y, Huang E, Huey ED, Kantarci K, Karydas A, Kaufer D, Knopman DS, Litvan I, Mackenzie IR, Mendez M, Onyike C, Petrucelli L, Ramos EM, Roberson ED,Rojas JC, Taraglia MC, Toga AW, Weintraub S, Forsberg LK, Heuer HW, Boeve BF, Boxer AL, Rosen HJ, Miller BJ, Moreno F, Seeley WW, Lee SE (2025). Functional connectivity associations with markers of disease progression in presymptomatic and symptomatic GRN mutation carriers. Annals Clinical Translational Neurology. 12(12):2575-2588.
Shen Y, Wong SZH, Ma T, Zhang F, Wang Q, Kawaguchi R, Geschwind DH, Wang J, He C, Ming GL, Song H (2025). m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice. Cell Stem Cell. 32(5): 727-743.
Trudler D, Ghatak S, Bula M, Parker J, Talantova M, Luevanos M, Labra S, Grabauskas T, Noveral SM, Teranaka M, Schahrer E, Dolatabadi N, Bakker C, Lopez K, Sultan A, Patel P, Chan A, Choi Y, Kawaguchi R, Stankiewicz P, Garcia-Bassets I, Kozbial P, Rosenfeld MG, Nakanishi N, Geschwind DH, Chan SF, Lin W, Schork NJ, Ambasudhan R, Lipton SA (2025). Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids. Molecular Psychiatry. 30(4):1479-1496.
Miller ZA, Ossenkoppele R, Graff-Radford NR, Allen IE, Shwe W, Rosenberg L, Olguin DJ, Erkkinen MG, Butler PM, Spina S, Yokoyama JS, Desikan RS, Scheltens P, van der Flier W, Pijnenburg Y, Wolters E, Rademakers R, Geschwind DH, Kramer JH, Rosen HJ, Rankin KP, Grinberg LT, Seeley WW, Sturm V, Perry DC, Miller BL, Rabinovici GD, Gorno-Tempini ML (20265. Neurodevelopment and neural environment inform Alzheimer’s disease age at onset and phenotype. Alzheimers Dementia. 21(9):e70668.
Schmitd LB, Hafner H, Ward A, Asghari Adib E, Biscola NP, Kohen R, Athaiya M, Tuttle M, Patel M, Williamson RE, Desai E, Bennett J, Saxman G, Wilborn D, Shumpert J, Zhao XF, Kawaguchi R, Geschwind DH, Hoke A, Shrager P, Collins CA, Havton LA, Kalinski AL, Giger RJ (2025). Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury. Science Translational Medicine. 17(819): eadp9155.
Gordon A, Yoon S-J, Bicks LK, Martin JM, Pintacuda G, Arteaga S, Wamsley B, Guo Q, Elahi L, Dolmetsch RE, Bernstein JA, O’Hara R, Hallmayer JF, Lage K, Pasca SP, Geschwind DH(2026). Developmental convergence and divergence in human stem cell models of autism. Nature. 651(8106): 707-719.