Publications

2006-2008

High density SNP association study of a major autism linkage region on chromosome 17

Stone JL, Merriman B, Cantor RM, Geschwind DH, Nelson SF (2007). High density SNP association study of a major autism linkage region on chromosome 17. Human Molecular Genetics. 16(6): 704-15.

Analysis of candidate genes at the IBGC1 locus associated with idiopathic basal ganglia calcification (“Fahr’s disease”)

Oliveira JRM, Sobrido MJ, Spiteri E, Hopfer S, Meroni G, Petek E, Baguero M, Geschwind DH (2007). Analysis of candidate genes at the IBGC1 locus associated with idiopathic basal ganglia calcification (“Fahr’s disease”). Journal of Molecular Neuroscience. 33(2): 151-4.

Identification of process-localized mRNAs from cultured rodent hippocampal neurons

Poon MM, Choi SH, Jamieson CA, Geschwind DH, Martin KC (2006). Identification of process-localized mRNAs from cultured rodent hippocampal neurons. Journal of Neuroscience. 26(51): 13390-9.

Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro

Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI (2006). Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 45(50): 15111-9.

Conservation and evolution of gene coexpression networks in human and chimpanzee brains

Oldham MC, Horvath S, Geschwind DH (2006). Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proceedings of the National Academy of Sciences USA. 103: 17973-17978.

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, Laurance MF, Zhao W, Qi S, Chen Z, Lee Y, Scheck AC, Liau LM, Wu H, Geschwind DH, Febbo PG, Kornblum HI, Cloughesy TF, Nelson SF, Mischel PS (2006). Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target. Proceedings of the National Academy of Sciences USA. 103(46): 17402-17407.

A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration

Karsten SL, Sang T-K, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH*, Jackson GR (2006). A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 51(5): 549-560. (*Co-corresponding author.)

Stratification based on language-related endophenotypes in autism: Attempt to replicate reported linkage

Spence SJ, Cantor RM, Chung L, Kim S, Geschwind DH, Alarcon M (2006). Stratification based on language-related endophenotypes in autism: Attempt to replicate reported linkage. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 141B: 591-598.

Gene expression profiling in frataxin deficient mice: Microarray evidence for significant expression changes without detectable neurodegeneration

Coppola G, Choi SH, Santos MM, Miranda CJ, Tentler D, Wexler EM, Pandolfo M, Geschwind DH (2006). Gene expression profiling in frataxin deficient mice: Microarray evidence for significant expression changes without detectable neurodegeneration. Neurobiology of Disease. 22 (2): 302-311.

FACS-array profiling of striatal projection neurons in juvenile and adult mouse brains

Lobo MK, Karsten SL, Gray M, Geschwind DH, Yang XW (2006). FACS-array profiling of striatal projection neurons in juvenile and adult mouse brains. Nature Neuroscience. 9(3): 443-452.