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Joined Lab – Sept 2023

Neelakshi Soni

Educational Background

Neelakshi Soni holds a Ph.D. in Mathematical, Computational and Systems Biology from the University of California, Irvine (2017-2023). Her research focuses on computational biology and bioinformatics, with a particular emphasis on neurodegenerative disorders. Neelakshi’s work involved investigating genetic and phenotypic overlap between various neurodegenerative conditions, developing computational pipelines for high-throughput sequencing data analysis, and integrating multi-omic data to identify patterns and biological pathways in complex biological phenomena. She applied machine learning and statistical analysis techniques to large-scale genomics datasets, with a focus on neuroimmunology and data analysis in the context of Alzheimer’s disease and other neurodegenerative conditions. Neelakshi developed and optimized bioinformatics tools for analyzing next-generation sequencing (NGS) data sets and performs cell-type enrichment analysis to identify specific cell populations in neurodegenerative contexts. Her expertise spans various programming languages and tools, including R, Python, and standard NGS bioinformatics toolsets, which she uses to analyze complex biological data and extract meaningful insights related to neurodegenerative diseases.

Research Focus

Neelakshi applies machine learning and statistical analysis techniques to large-scale genomics datasets, focusing on neuroimmunology and data analysis in the context of neurodegenerative conditions. Her work contributes to the lab’s efforts in mapping brain-relevant regulatory relationships by integrating data from various sources, including genetic variants, transcriptomics, chromatin accessibility, and epigenetic marks across human development. Neelakshi’s skills in programming languages such as R and Python, along with her expertise in standard NGS bioinformatics toolsets, enable her to analyze complex biological data and extract meaningful insights that contribute to the lab’s systems biology framework and multidisciplinary approach to understanding disease mechanisms. I am particularly excited about the opportunity to work with large, proprietary datasets to fine-tune innovative AI models.

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