December 5, 2016 – Brains of people with autism spectrum disorder share similar molecular abnormalities

The UCLA Newsroom made a press release for Nature paper by Parikshak et al. using gene expression data from RNA-seq in postmortem human brain to show changes in cortical patterning, gene regulation, and alternative splicing in ASD. The story was covered by Medical Xpress on December 5 and Technology.org on December 6. A diagram from Parikshak et al.’s paper is shown below depicting standard patterns for active genes in individuals with typical brains vs the patterns in the brains of individuals with autism.

Neelroop Parikshak/UCLA Health

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